Autosampler Vials & Closures

How do you choose the right autosampler vials and closures? There are 4 steps manufacturers universally agree will help you get to the right product.

Start with the closures

Screw thread closures are widely used for HPLC and LCMS. They’re easy, straightforward, and don’t require any special tools to use. They provide a better seal than snap tops, and are preferred when volatile solvents are involved.

Snap tops are a choice of convenience. If hundreds of samples need capping at once, it’s fast and easy. And if the diluent/solvent is water near room temperature, the snap top is just fine.

If your instrument requires a magnetic seal, crimp closures/caps are required.

*Hot tip - to reduce or eliminate problems making a proper seal, use an adjustable crimper.

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Find your vial material

As you know, borosilicate glass is the least reactive. It's the most common type of autosampler vial.


Polypropylene vials give you a good cost control option in certain circumstances - working with acetone, ethyl acetate, methanol, isobutyl alcohol, and methyl ethyl ketone.

Pick your size

Most autosampler vials are 2ml.


Vial inserts like these can reduce that volume as needed.

Amber or clear?

Like anywhere else in the lab, amber glass is suitable for light sensitive samples.


For everything else, clear is the standard.

Need help finding the appropriate autosampler vials and closures?

We have a massive offline catalog of products. If you can't quickly find what you need on our website, send us a quick message or call us here and we'll get you what you need or a suitable alternative.

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Your time is better spent in the lab. Not searching for supplies on Google.


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For our customers, it's a relief knowing this monotonous part of the job is done for them.

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And we have 80+ year relationships with many of your preferred manufacturers. Which means you get realistic and honest ETAs on product availability.


If the supply chain doesn't work with your timeline, we won't lead you on. We'll tell you, then find good alternatives that fit your need. So you don't have to waste time searching.


It saves you the legwork and keeps your lab productive when others are waiting for orders that are still 6-months away.


Tell us what you need. We'll tell you when you can actually get it, and give you the alternatives that can get to you sooner.

Find your autosampler vials and closures below. Or give us a call and drink a coffee while we'll do it for you.