Hamilton metal hub (N) needle assembly

The Metal Hub needles are designed for use with Hamilton PTFE Luer Lock (TLL) syringes and come in a range of gauges from 10 to 33. These needles meet ANSI standards for Luer connections and are compatible with male Luer fittings that adhere to this specification. Hamilton’s hub is specifically engineered to minimize dead volume, trapping around 10 µL of liquid - significantly less than the 70+ µL trapped by other designs. However, priming a 25 µL syringe with these needles can be challenging due to the minimal dead volume. To prevent clogging during transport, 27 to 33 gauge needles include a cleaning wire, which must be carefully removed before use.

Steps for assembling a metal hub needle onto a TLL syringe:

1. For small gauge needles (27–33), first remove the cleaning wire.
2. Attach the Metal Hub needle by pressing it gently onto the syringe’s Luer Lock fitting and turning it clockwise to secure the threads.

Hamilton Kel-F (KF) hub needle assembly

Kel-F Hub needles are compatible with various Hamilton products, including PTFE Luer Lock (TLL) and Luer Tip (LT) syringes, and are available in gauges ranging from 10 to 31. These needles adhere to the ANSI standard for Luer connections, making them suitable for use with male Luer fittings produced to this standard. Hamilton’s hub design minimizes trapped dead volume, reducing it to about 10 µL—significantly less than the 70+ µL found in other hub types. Despite this low dead volume, priming 10 and 25 µL syringes with these needles can be challenging. To prevent clogging during shipment, 27 to 33 gauge needles include a cleaning wire, which must be carefully removed before use.

Steps for assembling a metal hub needle onto a TLL syringe:

1. For small gauge needles (27–33), remove the cleaning wire.
2. To attach a Kel-F needle to an LT syringe, gently press it onto the Luer tip. For a TLL syringe, press the needle onto the Luer Lock fitting and rotate it clockwise to engage the locking threads.

Hamilton removable needle (RN) assembly

There are two types of removable needles: small hub and large hub. Small hub removable needles are designed for syringe volumes ranging from 2.5 µL to 100 µL and come in gauges from 18 to 34. Large hub removable needles are compatible with syringe volumes from 250 µL to 10 mL and are available in gauges from 20 to 26s. The removable needle is secured to the syringe by tightening the RN nut, which compresses a small plastic ferrule between the needle hub and the glass syringe barrel, ensuring a leak-free seal. For most removable needles, the needle hub is made of stainless steel, and the plastic seal is PTFE. For smaller gauge needles (27 to 34), a one-piece plastic ferrule made of CTFE is used. To prevent clogging during shipping, 27 to 33 gauge needles include a cleaning wire, which must be carefully removed before assembly.

Steps for assembling an RN syringe and needle:

1. If using a small gauge needle (27–33), remove the cleaning wire by gently straightening it and pulling by hand or with pliers.
2. Remove the RN nut from the syringe.
3. If the syringe has an existing needle, gently remove it by pulling out the needle, ensuring the plastic ferrule does not remain inside the syringe.
4. Insert the new needle and ferrule into the RN syringe termination.
5. Carefully thread the RN nut over the needle and tighten it onto the syringe.