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Karl Fischer Reagents & Standards

Karl Fischer Reagents in the Northeast US

Karl Fischer reagents are used to determine the moisture content of a sample. It’s a fast and easy method that requires only a small amount of sample.


Tips & Tricks: Karl Fischer Titration - Measuring Water Content of Samples that do not Easily Release Water

Moisture Measurement - Karl Fischer Titrimetry 2nd Edition


We stock Karl Fischer reagents primarily from GFS chemicals and MilliporeSigma. Our almost 100-years of experience tell us these are preferred by labs like yours because:


They’re the best value on the market

They have excellent product availability

They’re well regarded for consistent product quality

They’re backed by industry leading manufacturing processes


That’s all well and good. But…

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Water Standards & Buffers

Water Standards & Buffers

Drying Agents

Drying Agents

Coulometric Reagents

Coulometric Reagents

Volumetric Reagents

Volumetric Reagents

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Why get your Karl Fischer reagents from SECO?

Our job is to make your job easy.


We have near-century-long relationships with many of your preferred manufacturers. Which means you get realistic and honest ETAs on product availability.


Many of your essential Karl Fischer reagents are already in stock in our warehouse in Pennsylvania.


But if the reagents you need aren't in stock, and if the supply chain doesn't work with your timeline, we can get you good alternatives that fit your need. So you don't have to waste time searching.


It saves you the legwork and keeps your lab productive when others are waiting for orders that are still 6-months away.


Tell us what you need. We'll tell you when you can actually get it, and give you the alternatives that can get to you sooner.

Frequently asked Karl Fischer questions

Q: What is drift in Karl Fischer titration?
A: Drift is the moisture detected inside the vessel that doesn't come from your sample. Drift (background moisture) can occur when the vessel has been unused for a while and moisture has infiltrated and accumulated inside, or it may be the result of a leak that allows a small amount of moisture to enter the vessel regularly.


Q: What's the best Karl Fischer electrode?
A: The answer is subjective. But you can find electrodes and more here.


Q: What's the difference between coulometric and volumetric?
A: Volumetric titration is typically selected for samples in the 100 parts per million to 100% water content range, although sample analysis down 10 ppm water is possible. Coulometric titration is typically selected with a water content of less than 1%, although samples with water content up to 5% are possible.


Q: What's the difference between one component and two component Karl Fischer reagents?
A: One component Karl Fischer reagents are most commonly used. They are the least expensive. If your lab is on a budget, or performs frequent KF titrations, these are likely your preferred choice. If you need a greater accuracy, speedier titrations, or less frequent standardization, choose a two component system.


GFS Karl Fischer Standards and ReagentsGFS Karl Fischer Drying AgentsGFS Karl Fischer water standards
Reagents List for ASTM D664Reagents List for ASTM D2896