PFAS Testing Solutions
Analytical methods, workflow guidance, and PFAS-ready products
Support your PFAS testing program with method-aligned standards, solvents, columns, sample handling, and filtration products. This page provides a practical overview of PFAS testing and the most commonly used testing methods.
Why PFAS Testing Matters
PFAS are persistent chemicals found in water, soil, and industrial materials. Regulatory focus continues to increase for drinking water and environmental monitoring, and laboratories need methods that are sensitive, reproducible, and reliable.
Reliable PFAS data depends on the full workflow: sample collection, contamination control, extraction or direct analysis, LC-MS/MS performance, and trusted reference materials.
PFAS Methods and Products
EPA 1621
EPA Method 1621 (Jan 2024) estimates adsorbable organic fluorine (AOF) in aqueous matrices by combustion ion chromatography (CIC), supporting aggregate fluorine screening rather than targeted PFAS quantitation.
- Use case: Broad fluorinated content screening and triage for follow-up targeted testing.
- Typical matrix: Aqueous samples.
- Official method: EPA Method 1621 PDF
- EPA 1621 Products
EPA 8327
SW-846 Method 8327 (Rev 0, July 2021) is an LC/MS/MS determinative method for selected PFAS in prepared samples or extracts, validated in surface water, groundwater, and wastewater matrices.
- Use case: Wastewater and impacted environmental waters.
- Typical matrix: Non-drinking water matrices.
- Official method: EPA Method 8327 PDF
- EPA 8327 Products
ASTM 7979
ASTM D7979-20 is an LC/MS/MS standard test method for PFAS determination in water, sludge, influent, effluent, and wastewater matrices.
- Use case: Routine PFAS quantitation for industrial and municipal programs.
- Typical matrix: Water, sludge, influent, effluent, and wastewater workflows.
- Official method: ASTM D7979-20 page
- ASTM 7979 Products
EPA 533
EPA Method 533 (Nov 2019) is a drinking water method using isotope dilution, anion-exchange SPE, and LC-MS/MS, including short-chain PFAS that Method 537.1 does not cover.
- Use case: Drinking water compliance and monitoring programs.
- Typical matrix: Drinking water.
- Official method: EPA Method 533 PDF
- EPA 533 Products
EPA 537.1
EPA Method 537.1 (Version 2.0, March 2020) is an SPE LC/MS/MS method for selected PFAS in drinking water, with method validation data reported for reagent and drinking water matrices.
- Use case: Drinking water compliance and utility monitoring.
- Typical matrix: Drinking water.
- Official method: EPA Method 537.1 PDF
- EPA 537.1 Products
EPA 1633 / 1633A
EPA Method 1633A (Dec 2024) is an LC-MS/MS method for targeted PFAS analysis in aqueous, solid, biosolids, and tissue samples, including isotope dilution and extracted internal standard quantification approaches.
- Use case: Comprehensive environmental PFAS investigations.
- Typical matrix: Aqueous, solids, biosolids, and tissues.
- Official method: EPA Method 1633A PDF
- EPA 1633 Products
Build a More Reliable PFAS Workflow
- Use low-background reagents, standards, and clean sample handling materials to reduce contamination risk.
- Match products to method requirements for extraction, filtration, separation, and calibration.
- Strengthen QA/QC with method-relevant references, blanks, and control samples.
- Keep pace with evolving drinking water and environmental PFAS guidance.
Additional PFAS Resources
Regulatory context note: EPA finalized PFAS National Primary Drinking Water Regulation limits in April 2024 for specific PFAS analytes and mixtures. Method selection should be aligned to your matrix, program objective, and current local or federal requirements.
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